This online article from Raising Children Network’s Parent Guide to ASD Therapies describes and evaluates the use of atypical antipsychotic medications, such as risperidone, quetiapine, aripiprazole, ziprasidone and olanzapineto treat irritability, aggressive behavior, and self-injurious behavior in children on the autism spectrum. The medications were originally developed to treat schizophrenia and psychosis.

The article concludes that some studies have shown positive effects in treating behavior issues in autism, but that more long-term research is needed to compare positive effects to risks and side-effects. The article also warns that side-effects can include weight gain, drooling, involuntary tremors, tiredness, drowsiness, increased appetite, increased heart rate, and heart problems.

Raising Children Network is an information resource maintained by a partnership of agencies in Australia. Its website offers “evidence-based content you can trust on hundreds of topics about raising children and looking after yourself as a parent.” [Website]