Return to Search

Antidepresivos tricíclicos para los trastornos del espectro autista (TEA) en niños y adolescentes

Tricyclic Antidepressants for Autism Spectrum Disorders (ASD) in Children and Adolescents

By Hurwitz, Romy; Blackmore, Roger; Hazell, Philip; Williams, Katrina; Woolfenden, Susan


This online article, written in Spanish, summarizes a research review conducted to determine whether tricyclic antidepressants (TCAs) can be used to treat autism symptoms, as well as challenging behaviors and co-occurring mental health conditions in autism.

The review found three studies using two TCAs (tianeptine and clomipramine) with people on the autism spectrum. Evidence of positive impacts was limited and sometimes contradictory, and side effects were reported. The article concludes that more research is required before TCAs can be recommended for use with people on the autism spectrum.

This resource is available in English, French, Portuguese, and Spanish.

Cochrane is a “global independent network of researchers, professionals, patients, carers, and people interested in health.” [Website] The network reviews evidence about health treatments.

For full text or more information



This online article is in Spanish



Is there a mistake in this record?
Please email us at

ACT provides the resources gathered in the Autism Information Database as a service. We cannot guarantee the suitability or effectiveness of any of the resources listed. We caution all users to be critical consumers; see MedlinePlus Guide to Healthy Web Surfing. ACT reserves the right to remove or refuse a listing, at our discretion.