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Aripiprazole for Autism Spectrum Disorders (ASD)

By Hirsch, Lauren E.; Pringsheim, Tamara


This online article summarizes a research review conducted to determine whether aripiprazole, an antipsychotic medication, is an effective treatment for severe behavior problems in people on the autism spectrum. The article concludes that evidence suggests aripiprazole can improve behavior issues in the short term, but side effects such as weight gain and involuntary tremors are possible.

One study showed similar long-term relapse rates in the placebo and treatment groups, suggesting that periodic re-evaluation of efficacy may be necessary. In the full article, the authors suggest that it might be appropriate to consider discontinuation of aripiprazole after about 12 weeks of treatment.

This resource is available in English, Croatian, French, German, Spanish, and Tamil.

Cochrane is a “global independent network of researchers, professionals, patients, carers, and people interested in health.” [Website] The network reviews evidence about health treatments.

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This online article is in English


Cochrane Database of Systematic Reviews

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